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» FWyeth Pharmaceuticals forms Irish collaboration
Wyeth Pharmaceuticals forms Irish collaboration
Date published: 14/02/2006
Wyeth Pharmaceuticals has announced a
collaboration with Dublin-based Opsona
Therapeutics. The partnership will aim to discover and develop compounds to
treat inflammatory diseases, based on Toll-like receptor (TLR) targets.
Professor Luke O'Neill, co-founder of Opsona, said: "TLRs are critical
initiators of inflammation and have been implicated in the development of
chronic inflammatory diseases such as rheumatoid arthritis and systemic lupus
erythematosis, in addition to applications in other fields, including cancer
and vaccines. "Targeting TLRs with new drug candidates has tremendous potential
as a new approach to treat such diseases."
Under the agreement Wyeth
will make an upfront payment to Opsona and further payments will be paid on
meeting certain discovery and development milestones. Opsona will also take
royalties on potential product sales, but no details have been
disclosed.
Opsona chairman Dr Cormac Kilty said: "The scientific
expertise of Opsona coupled with the capabilities of Wyeth is a great
combination for drug discovery and development to bring new drugs into the
clinic for the treatment of these disabling diseases. "This collaboration also
reaffirms Wyeth's continued investment in the Irish biotechnology sector."
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